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1.
Interact Cardiovasc Thorac Surg ; 35(5)2022 10 10.
Article in English | MEDLINE | ID: covidwho-20233824

ABSTRACT

Aortic wrapping is a controversial repair in patients presenting with acute type A aortic dissection or intramural haematoma, but this method may be a potential alternative to medical treatment or conventional repair in patients aged >80 years and in those presenting with prohibitive co-morbidities such as stroke, circulatory collapse, full oral anticoagulation with the last generation drugs. We report on 5 high-risk and/or patients over 80 years who received external aortic wrapping with or without cardiopulmonary bypass during the last 18 months. All survived the procedure and could be extubated early postoperatively. No patient remained on the intensive care longer than 2 days and all were discharged without additional complications. Postoperative radiological control was acceptable and no patient had any new aortic event up to 18 months postoperatively.


Subject(s)
Aortic Aneurysm, Thoracic , Aortic Dissection , Humans , Aortic Dissection/complications , Aortic Dissection/diagnostic imaging , Aortic Dissection/surgery , Hematoma/diagnostic imaging , Hematoma/etiology , Hematoma/surgery , Aorta , Cardiopulmonary Bypass , Anticoagulants/therapeutic use , Treatment Outcome , Aortic Aneurysm, Thoracic/surgery
2.
Am J Case Rep ; 22: e928421, 2021 Feb 05.
Article in English | MEDLINE | ID: covidwho-1068018

ABSTRACT

BACKGROUND High-frequency percussive ventilation (HFPV) is a method that combines mechanical ventilation with high-frequency oscillatory ventilation. This report describes 3 cases of patients with severe COVID-19 pneumonia who received intermittent adjunctive treatment with HFPV at a single center without requiring admission to the Intensive Care Unit (ICU). CASE REPORT Case 1 was a 60-year-old woman admitted to the hospital 14 days after the onset of SARS-CoV-2 infection symptoms, and cases 2 and 3 were men aged 65 and 72 years who were admitted to the hospital 10 days after the onset of SARS-CoV-2 infection symptoms. All 3 patients presented with clinical deterioration accompanied by worsening lung lesions on computed tomography (CT) scans after 21 days from the onset of symptoms. SARS-CoV-2 infection was confirmed in all patients by real-time reverse transcription-polymerase chain reaction (RT-PCR) assay from nasal swabs. All 3 patients had impending respiratory failure when non-invasive intermittent HFPV therapy was initiated. After therapy, the patients had significant clinical improvement and visibly decreased lung lesions on followup CT scans performed 4-6 days later. CONCLUSIONS The 3 cases described in this report showed that the use of intermittent adjunctive treatment with HFPV in patients with severe pneumonia due to infection with SARS-CoV-2 improved lung function and may have prevented clinical deterioration. However, recommendations on the use of intermittent HFPV as an adjunctive treatment in COVID-19 pneumonia requires large-scale controlled clinical studies. In the pandemic context, with a shortage of ICU beds, avoiding ICU admission by using adjunctive therapies on the ward is a useful option.


Subject(s)
COVID-19/therapy , High-Frequency Ventilation , Aged , COVID-19/complications , Clinical Deterioration , Cough/therapy , Cough/virology , Dyspnea/therapy , Dyspnea/virology , Female , Hospitalization , Humans , Lung/diagnostic imaging , Lung/virology , Male , Middle Aged , Oxygen Inhalation Therapy , Respiratory Insufficiency/prevention & control , Tomography, X-Ray Computed
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